NY Yankees at Detroit 6:40 PM ET
Seemingly well on their way to claiming the best record in the majors, the New York Yankees were instead tripped up in stunning fashion by the worst team in baseball. After having their three-game winning streak snapped in a wild 12-11 setback, the Yankees look to get back on track when they resume their three-game series at the Detroit Tigers on Wednesday night.
LA Dodgers at Baltimore 7:05 PM ET
The Los Angeles Dodgers clinched the National League West crown for the seventh straight time and have loads of time to get themselves prepped for the playoffs. They begin that preparation in earnest Wednesday in the second of a three-game interleague series with the host Baltimore Orioles.
Atlanta at Philadelphia 7:05 PM ET
The Philadelphia Phillies host the Atlanta Braves for Wednesday’s third matchup of a four-game series, and hope the power from Tuesday’s 6-5 victory will show up again to help keep their flickering National League playoff hopes alive. The Phillies belted five homers Tuesday, including a go-ahead inside-the-park blast from center fielder Scott Kingery, after starting the day three games behind the Chicago Cu
Boston at Toronto 7:07 PM ET
The Boston Red Sox have already been eliminated from contention for the American League East title and are watching their slim hopes for a wild-card berth fade away as they stumble down the stretch. The defending World Series champions hope to avoid a fifth consecutive defeat when they resume their three-game series at the Toronto Blue Jays on Wednesday night.
Milwaukee at Miami 7:10 PM ET
The Milwaukee Brewers were dealt a crushing blow in their bid for a return to the playoffs after learning that reigning National League MVP Christian Yelich sustained a fractured right kneecap on Tuesday. The Brewers look to answer that jarring loss by notching their sixth straight win on Wednesday when they continue their four-game series against the host Miami Marlins.
Arizona at NY Mets 7:10 PM ET
The Arizona Diamondbacks won 11 of 12 contests to jump to the front of the line in a long list of contenders chasing the last wild card in the National League, only to fall short in each of their last three outings. The Diamondbacks aim to stop their skid on Wednesday as they play the third contest of their four-game series against the host New York Mets.
Washington at Minnesota 7:40 PM ET
The Washington Nationals are suddenly sputtering while trying to pull away in the National League wild-card race and look to start moving in a positive direction when they visit the Minnesota Twins for the middle contest of their three-game interleague series on Wednesday. The Nationals, who are third in the NL in runs scored, managed just two hits in the series-opening 5-0 setback Tuesday - their fifth loss in six games.
Tampa Bay at Texas 8:05 PM ET
The Tampa Bay Rays are not giving pursuers in the race for American League wild-card spots much help with 11 victories in 12 contests and can extend their winning streak to a season-high seven games when they visit the Texas Rangers on Wednesday. The Rays rallied to tie it in the eighth inning on red-hot Austin Meadows’ two-run homer and scored twice in the 11th for a 5-3 victory in Tuesday's series opener.
Cleveland at LA Angels 8:07 PM ET
The Los Angeles Angels hope to have superstar Mike Trout back in the lineup Wednesday for the finale of their three-game series against the visiting Cleveland Indians. The Angels have struggled at the plate without the two-time MVP, who has missed the last three games due to a nerve issue in his right foot.
Oakland at Houston 8:10 PM ET
The Oakland Athletics recovered from a 15-run setback to post a severe 14-run beating of their own while recording a season high for runs and equaling the franchise record of 25 hits. The visiting Athletics look to ride the momentum to another strong effort when they visit the Houston Astros for the third contest of their four-game series on Wednesday, one day after posting an impressive 21-7 triumph.
Kansas City at Chi. White Sox 8:10 PM ET
Yoan Moncada has picked on Kansas City throughout his breakout campaign, and he'll try to stay hot at the plate when his Chicago White Sox continue a three-game series with the visiting Royals on Wednesday. Moncada had three hits - including a two-run homer - in a 7-3 victory in the series opener Tuesday.
St. Louis at Colorado 8:40 PM ET
The St. Louis Cardinals look to bounce back from an unusually quiet night at Coors Field when they continue their three-game series against the Colorado Rockies on Wednesday. St. Louis had won five in a row against Colorado before managing just six hits in Tuesday’s 2-1 loss.
Pittsburgh at San Francisco 9:45 PM ET
The San Francisco Giants managed to withstand a late comeback attempt on Tuesday after succumbing to one in the series opener. They hope to have the opportunity to protect another lead when they host the Pittsburgh Pirates on Wednesday for the third contest of their four-game series.
Chi. Cubs at San Diego 10:10 PM ET
Cole Hamels grew up 25 miles away from Petco Park and has thrived in his returns to his hometown ballpark. The former star at Rancho Bernardo High looks to throw another gem when the Chicago Cubs visit the San Diego Padres on Wednesday for the third contest of their four-game series.
Cincinnati at Seattle 10:10 PM ET
The Seattle Mariners began their six-game homestand on Tuesday by ending their six-game losing streak in exciting fashion. The team attempts to post consecutive victories for the first time since a four-game winning streak from Aug. 17-20 when it hosts the Cincinnati Reds on Wednesday for the middle contest of their three-game interleague series.